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儿童脑干海绵状血管瘤(Cavernous Angiomas of the Brain Stem in Children)

编辑:INC|发布时间:2019-09-16 16:24|点击次数:
  Cavernous Angiomas of the Brain Stem in Children
  儿童脑干海绵状血管瘤
 
  英文摘要:
 
  Abstract Out of 27 children with intracranial cavernous angiomas observed in a 17-year period of time, 3 presented with their lesion located in the brain stem. A further 19 pediatric cases of brain stem cavernous angiomas sufficiently well described for a reliable analysis were collected from the literature and evaluated for the present study. The widespread use of MR imaging has significantly increased the possibility of recognizing brain stem cavernomas at an early age; indeed, their incidence is nowadays regarded to range between 9 and 15% of pediatric cavernous angiomas. A female predominance was noted in the present study. Focal neurological deficits are the most frequent presenting symptoms; they tend to occur acutely in most cases, although subsequent improvement may then be observed in several patients. Recurrent hemorrhages from the angioma result usually in heavier neurological signs. Surgical approaches have to be planned according to the location of the lesion, and to the site where the angioma is eventually in contact with the pial or ependymal surface. No surgical deaths were observed in these 22 children; only 2 patients presented a mild persistent worsening of their neurological status after the operation. These good results indicate that brain stem cavernous angiomas are actually a surgical lesion in spite of their apparently unfavorable location. The good prognosis is related to the anatomophysiological features of these lesions, which usually displace the brain stem structures rather than invade them, and are characterized by a low-pressure and slow blood flow circle.
 
  中文摘要:
  在27例颅内海绵状血管瘤患儿中,有3例病灶位于脑干。从文献中收集了另外19例脑干海绵状血管瘤的儿童病例,并对其进行了评估。磁共振成像的广泛应用大大增加了早期识别脑干海绵状瘤的可能性;事实上,他们的发病率目前被认为在儿童海绵状血管瘤的9 - 15%之间。在本研究中,女性占主要部分。局灶性神经功能障碍是较常见的症状;它们往往在大多数情况下发生剧烈,尽管随后的改善可以在几个病人中观察到。血管瘤复发性出血通常导致较重的神经症状。手术入路必须根据病变的位置和血管瘤最终与皮或室管膜表面接触的位置来计划。在这22名儿童中没有观察到手术死亡;仅有2例患者术后神经功能轻度持续恶化。这些良好的结果表明,脑干海绵状血管瘤虽然位置明显不适宜,但实际上是一种外科病变。预后良好与这些病变的解剖生理特征有关,这些病变通常是移位而非侵犯脑干结构,其特点是血压低、血流缓慢。
儿童脑干海绵状血管瘤(Cavernous Angiomas of the Brain Stem in Children)
  INC国际神经外科医生集团旗下组织世界神经外科顾问团(WANG)成员,世界神经外科联合会教育委员共同主席(2013-2017年)Concezio Di Rocco教授参与主要编写。Concezio Di Rocco教授在儿科神经外科及科领域的临床治疗经验颇为丰富,是国际公认的儿科神经外科专家。
 
儿童脑干海绵状血管瘤(Cavernous Angiomas of the Brain Stem in Children)
  Di Rocco教授曾受邀来我国参与了多场神经外科学术交流,将国际前沿的临床技术经验分享于我国神经外科医生,进一步拓展了国内儿科神经外科医生对国际领先技术和治疗策略的认识。除此之外,作为INC旗下世界神经外科顾问团(WANG)的知名人物,教授还在INC的组织协调下,在德国为中国的儿童神经外科患者提供相关的治疗服务。

INC国际神经外科医生集团,国内脑瘤患者治疗新选择,足不出户听取世界神经外科大咖前沿诊疗意见不是梦。关注“INC国际神经科学”微信公众号查看脑瘤治疗前沿资讯,健康咨询热线400-029-0925,点击立即预约在线咨询直接预约INC国际教授远程咨询!

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