
Abstract Background:In Parkinsons disease (PD), dopamine replacement therapy (DRT) enhances the effective connectivity of the prefrontal cortex (PFC) and supplementary motor area (SMA). The clinical effects of deep brain stimulation (DBS) o...

Abstract Introduction:The treatment of low-grade gliomas(LGGs)in pediatric age is still controversial.However,most authors report longer life expectancy in case of completely removed cerebral gliomas.Intraoperative magnetic resonance imagin...

Abstract Objective:The object of this study was to investigate the impact of facility type(academic center[AC]vs non-AC)and facility volume(high-volume facility[HVF]vs low-volume facility[LVF])on low-grade glioma(LGG)outcomes. Methods:This...

Abstract Background:Differentiating treatment-induced injury from recurrent high-grade glioma is an ongoing challenge in neuro-oncology in part due to lesion heterogeneity.This study aimed to determine whether different MR features were rel...

Abstract The importance of genomic information in intrinsic brain tumors is highlighted in the World Health Organization (WHO) 2016 classification of gliomas, which now incorporates both phenotype and genotype data to assign a diagnosis. By...

Abstract Background:There is paucity of information about the frequency of hydrocephalus prior to and after posterior fossa tumor surgery in adult patients and about the best way it should be managed.The present study was conducted to deter...

Abstract Background: Endoscopic resection of colloid cysts is a widely accepted treatment option instead of microsurgery.However,there is still a debate about a potentially higher rate of incomplete resections and recurrence. Objective: The...

Abstract Objective: Large experiences with the treatment of pediatric arteriovenous malformations(AVMs)remain relatively rare,with limited data on presentation,treatment,and long-term functional outcomes.Because of the expected long lifespa...

Abstract Abstract Background Various synthetic materials are used in neurosurgery and left in place intentionally during surgery for several purposes such as hemostasis,dural closure,or cranioplasty.Although leaving such substances in surgi...

Abstract The efficacy of treating malignant gliomas with adjuvant therapies remains largely unsuccessful due to the inability to effectively target invading cells.Although our understanding of glioma oncogenesis has steadily improved,the mo...